Roche and Garvan Institute of Medical
Research partner to develop epigenomics technology
19 August 2014
Roche and the Garvan Institute of
Medical Research in Australia are collaborating to develop new
accurately analyze regions of the epigenome using DNA sequencing.
brings together the world-leading genomics expertise and
infrastructure at the Garvan Institute and the best-in-class
products for target enrichment from Roche NimbleGen, part of the
Roche Sequencing Unit.
As part of the agreement, the SeqCap Target Enrichment System
from Roche will be used by scientists at the Garvan Institute to
further their research in epigenetic influences on human diseases.
“This is an excellent example of collaboration between a leading
edge company and research institute in the development of advanced
technology for genetic analysis, which will empower more research
into human biology and disease, and lead to many translational
opportunities,” said Professor John Mattick, Executive Director of
the Garvan Institute.
“In addition to our recent investments in sequencing platform
technologies, our research team is working closely with key opinion
leaders to advance sequencing applications of current and future
technologies,” said Tom Albert, Head of Research at Roche’s
Sequencing Unit. “This collaboration with the Garvan Institute
illustrates the potential of SeqCap Target Enrichment products in
additional sequencing applications for epigenetic research. This
brings us closer to delivering sequencing applications to the clinic
that offer truly differentiated medical value.”
Epigenetics is the heritable changes in gene expression that are
not caused by changes in the DNA sequence or genetic code, but
rather involve secondary chemical modifications of the DNA and the
structural proteins in chromosomes. It is being recognized as
playing an important role in a host of biological processes and
their role in cancer has been increasingly investigated. Due to the
myriad of epigenomic events responsible for influencing expression
of genes in chromosomes, more advanced methods are being sought to
accurately analyze these changes.