Vienna Prediction Model calculates risk of venous thrombosis
6 September 2013
Researchers at the Medical University of Vienna have developed a
model to calculate the risk of patients suffering a recurrence of a
venous thrombosis using three factors.
The three factors are: the patient’s gender, the location of the
thrombosis and a bio-marker known as the D-dimer, which is the
product of protein separation. The D-dimer level in the blood is of
major significance in the diagnosis or exclusion of deep venous
thrombosis and pulmonary embolisms, but also in predicting the risk
of the condition recurring.
In Austria, around 15,000 people a year develop a venous
thrombosis, the occlusion of a vein that can result in a pulmonary
embolism. A clot breaks free from a vein and travels via the
bloodstream to the lungs, where it blocks vessels.
The recurrence of a venous thrombosis or pulmonary embolism can
only be prevented through intensive treatment with clot-preventing
medications. Many patients are therefore advised to take long-term
therapy. This therapy, however, means the daily and in some cases
lifelong consumption of medications which also entail a major risk
of bleeding, which can sometimes even be fatal.
The model was developed as part of the world's largest study on
thrombosis, the Austrian Study on Recurrent Venous Thromboembolism