Oxford Nanopore announces further collaborations for nanopore sensing technology

13 February 2013

Oxford Nanopore Technologies has completed a series of agreements with leading academic research institutions, including the University of Illinois at Urbana-Champaign, Brown University, Stanford University, Boston University, University of Cambridge and the University of Southampton.

Oxford Nanopore has an intellectual property portfolio of more than 300 issued patents and patent applications in over 80 patent families. The Company is currently pursuing techniques for nanopore-based analysis using biological and solid-state nanopores, as well as hybrid versions of these, and also including a wide variety of adaptations and modifications.

The expanded intellectual property (IP) portfolio now covers a broad range of technologies, including:

  • DNA base identification using a biological nanopore;
  • addition of adapters to nanopores for sensing;
  • genetically modified nanopores for sensing;
  • combining nanopores and enzymes for sensing;
  • use of molecular motors in combination with nanopores;
  • localising polymerases to a surface, including pore-bound localisation;
  • use of solid state nanopores for detecting labelled ssDNA and dsDNA;
  • use of solid state devices to control movement of polymers;
  • detection and positional measurement of probes on a DNA strand as the strand passes through a nanoscale detector;
  • methods of fabricating solid-state nanopores including multi-layered devices; and
  • the use of functionalised solid-state nanopores for molecular characterisation, including graphene, tunnelling currents and nanotubes.

Dr Gordon Sanghera, CEO of Oxford Nanopore, said, "Oxford Nanopore has invested substantial resources into building its expertise, know-how and intellectual property portfolio that will support our leadership in nanopore sensing technologies. The collaborations announced today add to our existing positions in core areas spanning current and future generations of nanopore technology. We are pleased to support further innovation in the laboratories of our collaborators, to complement the pioneering work being performed by our own interdisciplinary R&D staff.


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