EU SKINSPECTION project develops hybrid multimodal 3D imaging system
18 April 2012
The EU-funded SKINSPECTION project has developed a novel multimodal hybrid diagnostic imaging system with the capability to perform non-invasive high resolution three-dimensional imaging in-vivo.
The SKINSPECTION approach combines two-photon imaging with time-correlated single photon detection, autofluorescence lifetime imaging, high-frequency ultrasound and optoacoustic imaging.
The innovative combination of these modalities allows to obtain a wide-field view with quantitative depth information of skin lesions and a close-look into particular intra-tissue compartments with quantitative hyperspectral information and subcellular resolution.
The goal of the project is to provide a novel unique tool for early diagnosis and treatment control of skin cancer and skin disease. For achieving this objective, two systems for microscopic and macroscopic imaging of lesions were developed in the last three years by the project partners JenLab GmbH and Imperial College London (two-photon microscopy/FLIM) and Fraunhofer IBMT (Fraunhofer Institute for Biomedical Engineering) and kibero GmbH (optoacoustic/ultrasound imaging).
The systems were successfully certified for clinical studies and are currently being evaluated for imaging of skin lesions in a bicentric clinical trial at Hammersmith Hospital, London and Universita di Modena.
Project website: www.skinspection-fp7.eu