Axela introduces assay kits for validating tumour markers
24 April 2009
Axela Inc. has launched nine plate based tumour marker assays.
Available in high performance ELISA format they have been designed for
stand alone use or to simplify the transition to automated dotLab
assays. Used in conjunction with Axela’s panelPlus biomarker menu
(available for the dotLab system this summer) this unique approach has
the potential to significantly transform the speed with which putative
biomarkers can be validated.
The following RUO (research use only) immunoassay kits for
quantitative determination of cancer antigens are available immediately:
alpha-fetoprotein (AFP); carcinoembroyonic antigen (CEA); CA125; CA15-3;
CA 19-9; PSA; free PSA (f-PSA); free beta subunit of human chorionic
gonadotropin (free beta-hCG) and beta-2 Microglobulin (B2MG).
In order to facilitate assay validation and simplify multiplexing the
panelPlus biomarker menu will incorporate the same capture reagents as
these ELISA kits. The ability to observe multiple analytes in real-time
provides a wider detection range than previously available.
Offering significant advantages over end point techniques, the dotLab
System allows creation of highly targeted and flexible biomarker panels
using these self addressing reagents. Scientists will be able to select
from the menu of analytes, and incorporate their own proprietary
reagents using the panelPlus address kit. Novel discoveries can be
compared directly to markers with known utility without increasing
sample volume requirements.
Axela is extending the versatility of the dotLab System by providing
biomarker assay and validation tools that complement its ability to
perform interaction studies, expression monitoring and analysis of
These new, easy to use, robust ELISAs will help researchers
quantitate cancer biomarkers in basic and clinical research settings and
will be followed by a selection of cardiology and infectious disease
targets. They are available through VWR Life Science in North America
and Axela in Europe
Bookmark this page