NanoKTN and Bionano Consulting partner to develop bionano and
nanomedicine in UK
20 October 2008
The Nanotechnology Knowledge Transfer Network (NanoKTN), the UK’s
primary knowledge-based network for Micro and Nanotechnologies, has
announced a 20-month partnership with Bio Nano Consulting (BNC) and the
creation of the NanoKTN’s fourth theme, Bionano and Nanomedicine.
This new partnership will support all UK bio-nanotechnology
capabilities and provide thought leadership and input into UK Government
policy and strategy related to bio-nanotechnology. The BNC and NanoKTN
will promote technology transfer and communication between researchers
and industry and encourage debate amongst interested parties regarding
the key ethical issues surrounding the potential impact of
nanotechnology and nanomedicine.
The NanoKTN and BNC will launch and coordinate at least four focus
groups per year, all dealing with a variety of Bionano and Nanomedicine
related topics, such as drug delivery and discovery, nano biosensors and
biomedical electronics. In addition it aims to organise one major annual
flagship event with the first one scheduled for early 2009 to cover
Nanotechnology and Regenerative Medicine.
This partnership between the NanoKTN and BNC includes the secondment
of Dr Mike Fisher, to the role of Theme Manager. As Theme Manager, Mike
Fisher will be responsible for managing the day-to-day operational
activities of the Bionano and Nanomedicine theme for the NanoKTN.
Most recently, Fisher worked for UK Trade & Investment as the UK
government’s Life Science Industry Advisor covering North America,
leading market analysis and intelligence projects, identifying
opportunities and threats to international investment, and representing
the UK regulatory agencies in the US. Fisher has written numerous
published papers, the most recent paper concerning early stage clinical
trials in the UK.
“I am delighted to be associated with an innovative organisation that
is contributing to the global growth and importance of nanotechnology,
particularly in the healthcare and life science sectors. This project
will raise the awareness of Bionano and Nanomedicine and support the
next generation of its capabilities,” explains Mike Fisher. “With so
many recent and positive developments in Bionano and Nanomedicine, this
is the right time for the NanoKTN to be promoting and supporting this
area of work. This is an extremely exciting opportunity.”
BNC is jointly owned by University College London (UCL) and Imperial
College and was founded in 2005 as part of the UK Department for Trade
and Industry (now Technology Strategy Board) Micro & Nano Technology (MNT)
initiative. To date BNC has received almost £5 million in government
funding to create and operate a Bio-nanotechnology centre of excellence.
As part of the original remit of the BNC, it was stipulated that they
participate in the creation and management of a UK Bio-Nano Network. As
this is the purpose behind the NanoKTN’s Bionano and Nanomedicine theme,
BNC is ideally suited to handle this contract.
Director of the NanoKTN, Dr Alec Reader comments, “Working with the
BNC has many benefits and I am looking forward to seeing this theme
evolve. Mike Fisher’s wealth of contacts in the Bionano and Nanomedicine
space will be invaluable to the NanoKTN.” Reader concludes, “This is a
great opportunity for us to promote the positive work of the UK Bionano
and Nanomedicine sector.”
Bionano and Nanomedicine is being widely used commercially with
positive affect. A US biotech company Abraxis developed a
chemotherapeutic drug for lung, ovarian and breast cancer being sold
under the trademark Abraxane. Abraxane is the first albumin-bound taxane
particle of approximately 130 nanometers that takes advantage of
albumin, a natural carrier of water-insoluble molecules (eg various
nutrients, vitamins, and hormones) found in humans. Abraxane is a first
in its class of drugs using the nanoparticle albumin bound (nab)
technology platform.
Abraxane is an innovative therapy that has been approved by the
United States Food and Drug Administration (FDA) for the treatment of
patients with breast cancer, after failure of combination chemotherapy
for metastatic disease or relapse within 6 months of adjuvant
chemotherapy, with prior therapy including an anthracycline unless
clinically contraindicated.
The formulation of Abraxane eliminates the need for premedication
with steroids and antihistamines for hypersensitivity reactions and is
delivered in just 30 minutes, compared to three hours for previous
drugs. The overall response rate with Abraxane for all study patients
was 21.5% compared to 11.1% with solvent-based alternatives.
Established by the Technology Strategy Board, the NanoKTN is managed
by the Centre for Process Innovation Ltd, a leading technology
development and consulting company.
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